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by: Aracely Jenkins

Genetics BIOL 3110

Aracely Jenkins
GPA 4.0

Mack Crayton

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Mack Crayton
Class Notes
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This 13 page Class Notes was uploaded by Aracely Jenkins on Thursday October 29, 2015. The Class Notes belongs to BIOL 3110 at Xavier University of Louisiana taught by Mack Crayton in Fall. Since its upload, it has received 21 views. For similar materials see /class/231004/biol-3110-xavier-university-of-louisiana in Biology at Xavier University of Louisiana.


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Date Created: 10/29/15
Genetics Lecture Exam 3 Study Outline Chapters 9 Molecular Structure of DNA and RNA Problem Sets p242245 Answers to all Conceptual Questions Molecular Genetics Functions of Genetic Material Information Storing Transmittable Replicable Erwin Chargaff Chargaff s Rule Base Chromatography Frederick Grif th Pneumococci Strains R amp S Mice Transmission Transformation Principle Avery MacLeod and McCarty Pneumococci Strains R amp S Enzymes Antibody IIR cells IIIS DNA Extract Figure 93 IHS DNA Extract No Enzymes DNase RNase protease negative control positive control Hershey and Chase DNAGenetic Material T2 phage electron microscopy Radioactive Isotopes Sulfur Phosphorus Linus Pauling Alpha Helix Structure Ball and Stick Models Rosalind Franklin and Maurice Wilkins XRay Diffraction Characteristics of DNA Helical MultiStranded lOBase Pairs per Turn and 34 nm Watson and Crick Double Helix Structure Ball and Stick Models Base Interaction Nucleic Acid Structure Nucleoside Pentose Sugar Nitrogenous Base Nucleotides Phosphate Group Pentose Sugar Glycosidic Bonds Nitrogenous Base adenine thymine cytosine guanine Single Strand phosphodiester Bonds directionality right Handed Double Helix 2nm antiparallel hydrogen bonding base stacking minor and major grooves 3D Structures histone nucleosome RNA Structure one stranded short length Amino Acid Structure peptide bond Chapter 10 Chromosome Organization and Molecular Structure Problem Sets p 267269 Answers to all Conceptual Questions Genetic Material Genome Chromosomes DNA Sequences 2nm RNA Synthesis Protein Synthesis Chromosome Separation Chromosome Compaction Virus Host Range Host Cells Structure selfassembly directed assembly host cell assisted assembly lipid bilayer envelope capsid protein coat viral genome positive sense negative sense Bacterial Chromosome nucleoid region intergenic region structural gene sequences Structure loop domains supercoiling negative vs positive function DNA gyrase Topoisomerase I Prokaryotic genes vs Eukaryotic genes Eukaryotic Chromosomes Structure Nucleosome llnm histone octamer histone protein histone code hypothesis chromatin remodeling radial loops nuclear matrixscalTolding matriXor sca old attachment regions MARsSARs chromosome territory euchromatin 300nm heterochromatin 700nm Constitutive Facultative Metaphase Chromosomes l400nm Structural maintenance of chromosomes proteins SMC condensin cohesin phase activity SegregationReplication DNA Sequences Origins of Replication Telomeres Centromeres Repetitive Sequences Genome Size vs Repetitions vs Complexity vs Renaturation Rate Uniquenonrepetitive Moderately Repetitive Highly Repetitive Chapter 11 DNA Replication Problem Sets p 293295 Answers to all Experimental Questions DNA Replication template strands daughter strands parental strands Meselsin amp Stahl nitrogen Isotopes semiconservative model Other Replication Models conservative dispersive Huberman amp Riggs Eukaryotic Chromosomes multiple origins of replication Eukaryotic DNA Replication Origins of Replication direction of synthesis replication fork autonomously replicating sequence prereplication complex preRC origin recognition complex ORC MCM helicase DNA ligase DNA replication licensing DNA gyrase Topoisomerase 11 DNA binding proteins RNA primase RNA primers primosome DNA polymerase I II ampIII families polymerase switch leading stand lagging strand okazaki strand Proofreading Mechanism High Fidelity Instability of mismatched pairs DNA con guration at active site induced f1t Proof reading DNA polymerase exonuclease baseexcision repair DNA Sequence Mutations point silent missense nonsense frameshift Telomeric Sequences telomerase bindingpolymerization translocation Chapter 12 Gene Transcription and Modification Problem Sets 320321 Answers to all Experimental Questions Central Dogma Gene Expression Transcription coding strand sense strand messenger RNA mRNA base sequences codons ribosomal binding site transcription factors tansacting elements cisacting elements Initiation direction on synthesis Regulatory elements enhancers silencers Promoter regulatory elements TATA box transcriptional start site core promoter basal transcription Elongation Termination RNA transcript functions Eukaryotic RNA Polymerases RNA pol I RNA pol 11 RNA pol III RNA Modi cation colinearity exons introns excise RNA splicing small nuclear RNA small nuclear ribonucleoproteins premRNA heterogeneous nuclear RNA spliceosome small nuclear RNA and a set of proteins capping polyA tail Genetics Lecture Exam 2 Study Outline Chapters 4 partial Extensions of Mendelian Inheritance Problem Sets p9499 Answers to all Conceptual Questions Types of Mendelian Inheritance Involving Single Genes Simple Mendelian Inheritance Law of Segregation Law of Independent Assortment Xlinked Incomplete Dominance Codominance Pleiotropic Effects Overdominance hetero zygote advantage Lethal Alleles essential gene nonessential gene conditional lethal alleles temperature sensitive alleles semi lethal alleles EXpressivity environmental effect Variable eXpressivity Incomplete Penetrance Complimentation Gene Interactions gene pathway twogene interaction modifying genes Epistasis intergenetic suppressors Chapter 5 Linkage and Genetic mapping in Eukaryote Problem Sets p125l32 Answers to all Conceptual Questions Linkage linkage group linked amp unlinked genes gene linkage map map distancecentriMorgan Recombination Creighton and McClintock frequency of recombination parental type recombinant type two and three point testcrosses Mitotic Recombination twin spotting Chapter 2 ChiSquared Problem Sets p4243 Answers to all Experimental Questions Problem Sets p 129 132 Answers to all Experimental Questions null hypothesis goodness of t degrees of freedom p values monohybrid cross dihybrid cross Chapter 7 NonMendelian Inheritance Problem Sets p182186 Answers to all Conceptual Questions Epigenetic Inheritance Mosaicism dosage compensation Xinactivation Lyon hypothesis barr body feline coat inheritance Chapter 8 Variations in Chromosome Structure and Number Problem Sets p216220 Answers to all Conceptual Questions Chromosome Anatomy p arm q arm metacentric submetacentric acrocentric telocentric Chromosome Staining homologous chromosomes GbandingGiemsa staining banding Changes in Chromosome Structure mutations Abnormal Crossovers Deletion terminal interstitial Duplication gene redundancy Inversion paricentric paracentric Polyploidy Aneuploidy Turner Syndrome Klinefelter Syndrome Trisomy 21 Familial Down Syndrome Nondisjunction Robertsonian Translocation Cridu chat Syndrome Inversion Loops acentric fragment dicentric chromosome Translocation Simple Translocation Reciprocal Translocation Gene Family ancestral gene paralogs homologous genes Genetics Lecture Exam 1 Study Outline Chapter 1 Overview of Genetics Fields of Genetics Transmission Genetics heredity genes alleles traits morphological psychological behavioral codominance incomplete dominance Molecular Genetics cellular composition nucleic acid proteins carbohydrates lipids ribonucleic acid deoxyribonucleic acid nucleotides The Human Genome Project chromosomes diploid haploid homologous gene expression environment Population Genetics genetic variation morphs gene mutations changes in chromosomal structure changes in chromosomal number Chapter 2 Mendelian Inheritance Mendel39s Experiments pea plants hybridization homozygous heterozygous phenotype genotype selffertilization crossfertilization test cross truebreeding variants monohybrid cross dihybrid cross Mendel39s Law of Segregation dominant recessive Mendel39s Law of Independent Assortment Punnett Squares genotypic ratio phenotypic ratio nonparentals forkedline method Patterns of Heredity Multiple Alleles Incomplete Dominance Pedigrees loss of function alleles cystic brosis colorblindness Probability and Statistics random sampling error sum rule product rule binomial expansion multinomial expansion Chapter 3 Reproduction and Chromosome Transmission Chromosomes proteins chromatin chromatids sisters prokaryotes nucleoid eukaryotes Cytogenetics somatic germ gamete karyotype loci locus restriction points mitotic spindle apparatus Cellular DiVision asexual reproduction multicellularity binary ssion cytokenesis cell plate Mitosis Interphase Gap 1 S phase Gap2 Prophase Prometaphase Metaphase metaphase plate spindle bers Anaphase Telophase Sexual Reproduction fertilization gametogenesis spermatogenesis spermatogonial cell primary spermatocyte acrosomal cap oogenesis asymmetric oogonia primary oocyte secondary oocytes polar body isogamous heterogamous Meiosis I Prophase Leptotena Zygotena synaptonemal complex synapsis Pachytena crossing over Diplotena tetrad bivalent Diakenesis Sex Determination autosomes sex chromosomes heterogametic homo gametic Thomas Hunt Morgan s fruit ies Xlinked Alleles reciprocal cross Disorders Down Syndrome Nondisjunction Trisomy


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