New User Special Price Expires in

Let's log you in.

Sign in with Facebook


Don't have a StudySoup account? Create one here!


Create a StudySoup account

Be part of our community, it's free to join!

Sign up with Facebook


Create your account
By creating an account you agree to StudySoup's terms and conditions and privacy policy

Already have a StudySoup account? Login here

Class Notes 1-20-15

by: Allie Newman

Class Notes 1-20-15 BSC 215

Marketplace > Biology > BSC 215 > Class Notes 1 20 15
Allie Newman
GPA 4.0
Anatomy and Physiology
Jason Pienaar

Almost Ready


These notes were just uploaded, and will be ready to view shortly.

Purchase these notes here, or revisit this page.

Either way, we'll remind you when they're ready :)

Preview These Notes for FREE

Get a free preview of these Notes, just enter your email below.

Unlock Preview
Unlock Preview

Preview these materials now for free

Why put in your email? Get access to more of this material and other relevant free materials for your school

View Preview

About this Document

Blood System, class notes 1-20-15
Anatomy and Physiology
Jason Pienaar
One Day of Notes
25 ?




Popular in Anatomy and Physiology

Popular in Biology

This 5 page One Day of Notes was uploaded by Allie Newman on Tuesday January 20, 2015. The One Day of Notes belongs to BSC 215 at a university taught by Jason Pienaar in Fall. Since its upload, it has received 140 views.

Similar to BSC 215 at University


Reviews for Class Notes 1-20-15


Report this Material


What is Karma?


Karma is the currency of StudySoup.

You can buy or earn more Karma at anytime and redeem it for class notes, study guides, flashcards, and more!

Date Created: 01/20/15
Allie Newman BSC 216 Class Notes 12015 Blood System The Circulatory System Circulatory system 0 Heart Blood vessels amp Blood Cardiovascular system 0 Heart amp Vessels o Hematology Study of Blood Blood 0 Only liquid connective tissue Formed elements cells platelets extracellular matrix plasma 0 Functions 0 Transport 0 Protection 0 Regulation 0 Components 0 Plasma 4763 volume Fibrinogen Serum water amp proteins 0 Buffycoat1 volume Platelets Neutrophils Eosinophils Basoths Lymphoctes Monocytes o Hematocrit3752 volume Erythrocytes Blood Synthesis Plasma 92 Water obtained from body tissue cells and intestines Proteins Most produced in m o Albumins globulins brinogen 0 V globulins produced by plasma cells 0 Originate in bone marrow circulate in bloodstream Blood Synthesis Formed Elements 0 Each day we produce 0 400 billion Platelets thrombocytes o 200 billion Erythrocytes red blood cells 0 10 billion Leukocytes Hemopoiesis stem cell 0 White blood cells lymphocyte Hemopoiesis the synthesis of blood Hemopoietic Tissues tissue that makes blood Hemopoietic Tissues o Yolk sac 0 Blood islands produce stem cells that colonize bone marrow liver spleen amp thymus Red bone marrow o Produces all 7 formed elements after birth mzeoid hemopoiesis o Lymphatic tissues 0 Thymus tonsils lymph nodes spleen mucous membranes 0 Produces Lymphocytes lymphoid hemopoiesis Blood Synthesis Erythrocytes Expression of receptors for Erythropoietin Erythropoietin stimulates erythrobasts to multiplyamp produce hemoglobin Nucleus amp organelles shrivel and are expelled from the cell to form reticuocytes Reticulocytes leave bone marrow polyribosomes disintegrate to become ervthrocvtes Summary 0 Hemopoietic stem cell l Erythrocyte colony forming unit l Erythroblasts l Reticulocytes l Erythrocytes see slide for helpful picture Blood Synthesis Iron Metabolism 6 steps 0 1 Mixture of Fe3 Fe2ingested 2 Stomach acid converts Fe3 to Fe2 3 Fe2 binds to gastroferritin in the stomach 4 Fe2 released in small intestine by gastroferritin 5 Fe2 binds to transferrin in blood plasma in the blood stream 6 Transferrin in liver Some release iron to be stored as a complex with aooferritin ferritin Ferritin protein how we store iron by releasing iron into blood stream when needed 0 Rest circulates to bone marrow hemoglobin production and muscles myoglobin production OOOOOO Blood Plasma 0 Liquid extracellular matrix yellow in color 0 92 Water 8 proteins nutrients glucose electrolytes hormones nitrogenous waste amp dissolved gases C02 0 Proteins o Albumin Most abundant Transports solutes amp hydrophobic hormones Affects viscosity amp osmolarity o Globulins d B globulins Solute amp Hormone transport Clotting v globulins Immunity antibodies 0 Fibrinogen Precursor to brin framework for blood clots o All except y Gobuins produced in the Liver 0 Blood Viscosity 0 Resistance to ow Particle cohesion Erythrocytes amp Plasma proteins 0 Blood Osmolarity o Semi permeable capillary walls Impermeable dissolved particles Sodium ions Plasma Proteins amp Erythrocytes Formed Elements 0 Cellular 0 Red blood cells Erythrocytes transport oxygen and carbon dioxide 56 million 0 Functions 0 Carry 02 from lungs to tissues 0 Carry C02 from tissues to lungs 0 Form 0 Lack nucleus mitochondria amp other organelles 0 Cannot divide No nucleus 0 Cannot aerobically respire No mitochondria Only glycolysis anaerobic o Erythrocyte cytoplasm 33 hemoglobin solution 0 Oxygen transport 0 Some C02 transport amp buffering o Carbonic Anhydrase Enzyme C02 H20 gt H2CO3 Majority of C02 transported like this 0 Spectrin amp Actin Cytoskeletal proteins Resilience amp durability 0 White blood cells Leukocytes function for defense and immunity 5000 10000 Basophils I Eosinophils I Neutrophils Lymphocytes Monocytes Platelets blood clotting 250000 400000 Hemoglobin 4 protein chains globins 2d 28 bound by ionic bonds quaternary structure 0 Each globin conjugates withl nonprotein heme moiety m of heme binds oxygen 02 reversibly Globin can also bind 5 of C02 Hemoglobin Variation 0 975 of adult hemoglobin 0 2d 28 globins HbA 25 of adult hemoglobin 0 2d 26 globins HbA2 Fetal Hemoglobin 0 2d 2v globins HbF o Binds oxygen more strongly Erythrocyte Life Cycle 0 1 Nutrients gathered Iron Amino acids 0 2 Negative feedback Homeostasis I hypoxemia Erythropoietin 3 Erythrocytes synthesized in red bone marrow 4 Erythrocytes Circulate for 120 days red blood cells take on a different shape 0 5 Spectrin deteriorates cannot be replaced or maintained Spleen channel destruction 0 6 Hemolysisl o Membrane fragments phagocytized o Hemoglobin disposal Macrophages separate heme from globin o Heme o Macrophages remove iron for reuse 0 Globin o Hydrolysed to amino acids 0 Rest of heme converted to biiverdin green and Bilirubin yellow 0 Bilirubin binds to albumin transported to liLer released into Bile ducts accumulates in gall bladder o Secreted into Feces amp Urine Clicker Quiz 0 1 Each hemoglobin molecule in the blood can carry a maximum of FOUR oxygen 02 molecules 0 2 Myeloid hemopoiesis refers to formed element synthesis in THE RED BONE MARROW o 3 Which of the following are physiological mechanisms for transporting C02 from tissues to the lungs ALL OF THE FOLLOWING 0 C02 DISSOLVES IN THE BLOOD PLASMA AS IS 0 C02 BINDS TO THE GLOBIN COMPONENTS OF HEMOGLOBIN o CARBONIC ANYDRASE IN THE o 4 In order to get to the bone marrow for hemopoesis speci cally heme production ferrous ions are transferred amongst GASTROFERRITIN AND TRANSFERRIN 5 What is the buffy coat THE THINNEST LAYER IN A CENTRIFUGED SMAPLE OF BLOOD AND THE LAYER THAT CONTAINS THE WHITE BLOOD CELLS LEUKOCYTES AND PLATELETS Erythrocyte Disorders 0 Any imbalance between Erythropoiesis amp Hemoysis 0 RBC excess Polycythemia 0 RBC de ciency Anemia Inadequate synthesis Hemorrhagic anemia o Hemolytic anemia Quantifying Erythrocytes amp Hemoglobin Three clinical measures 0 RBC counts Hemoglobin amp Hematocrit 0 Determine 02 carrying ability Hematocrit blood volume RBC count 0 Flow cytometery I Hemoglobin Dehydration Polycythemia 0 Primary polycythemia 0 Cancer of red bone marrow Secondary polycythemia o All other causes emphysema excessive aerobic exercise high altitude smoking Increases blood volume viscosity amp pressure 0 Cardiac strain


Buy Material

Are you sure you want to buy this material for

25 Karma

Buy Material

BOOM! Enjoy Your Free Notes!

We've added these Notes to your profile, click here to view them now.


You're already Subscribed!

Looks like you've already subscribed to StudySoup, you won't need to purchase another subscription to get this material. To access this material simply click 'View Full Document'

Why people love StudySoup

Steve Martinelli UC Los Angeles

"There's no way I would have passed my Organic Chemistry class this semester without the notes and study guides I got from StudySoup."

Jennifer McGill UCSF Med School

"Selling my MCAT study guides and notes has been a great source of side revenue while I'm in school. Some months I'm making over $500! Plus, it makes me happy knowing that I'm helping future med students with their MCAT."

Bentley McCaw University of Florida

"I was shooting for a perfect 4.0 GPA this semester. Having StudySoup as a study aid was critical to helping me achieve my goal...and I nailed it!"


"Their 'Elite Notetakers' are making over $1,200/month in sales by creating high quality content that helps their classmates in a time of need."

Become an Elite Notetaker and start selling your notes online!

Refund Policy


All subscriptions to StudySoup are paid in full at the time of subscribing. To change your credit card information or to cancel your subscription, go to "Edit Settings". All credit card information will be available there. If you should decide to cancel your subscription, it will continue to be valid until the next payment period, as all payments for the current period were made in advance. For special circumstances, please email


StudySoup has more than 1 million course-specific study resources to help students study smarter. If you’re having trouble finding what you’re looking for, our customer support team can help you find what you need! Feel free to contact them here:

Recurring Subscriptions: If you have canceled your recurring subscription on the day of renewal and have not downloaded any documents, you may request a refund by submitting an email to

Satisfaction Guarantee: If you’re not satisfied with your subscription, you can contact us for further help. Contact must be made within 3 business days of your subscription purchase and your refund request will be subject for review.

Please Note: Refunds can never be provided more than 30 days after the initial purchase date regardless of your activity on the site.