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Mitosis Specifics

by: Matt Pawlush

Mitosis Specifics BIOSCI0716

Marketplace > Biology > BIOSCI0716 > Mitosis Specifics
Matt Pawlush
GPA 101.3
Biology II
Dr. Curto

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About this Document

Specifics involved with mitosis
Biology II
Dr. Curto
One Day of Notes
25 ?




Popular in Biology II

Popular in Biology

This 2 page One Day of Notes was uploaded by Matt Pawlush on Friday January 23, 2015. The One Day of Notes belongs to BIOSCI0716 at a university taught by Dr. Curto in Fall. Since its upload, it has received 334 views.


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Date Created: 01/23/15
MITOSIS Three functions that use mitosis in cell life gt Growth Is especially apparent in multicellular organisms When cells need replaced Wound repair Reproduction Early gamete formation in Eukaryotes The goal of Mitosis is to accurately separate and distribute Replicated DNA and Cytoplasm Duplicated chromosomes are held together by Cohesins Normally loose and Wispy chromatin is packed tightly together into the tradition chromosome X shape Recently discovered functions of histones include Regulation of gene expression DNA repair Cancer inhibition Histone Tails Amino termini of histones project out of the nucleosome core and interact With DNA The histone tails can be modified and can also function as signals Epigenetics Histone Code Epigenetic Control Inherited changes in phenotype or gene expression caused by mechanisms other than changes in the underlying DNA sequence DNA itself may be methylated to cause a decrease in gene expression Along With DNA being wrapped around the histones loops containing the DNAhistones are formed and this further compacts the loose DNA These loops are held together by CONDENSINS Supercoiling also occurs Supercoiling in DNA is similar to What happens When you twist a rubber band tightly and it coils back on itself Centrosomes send microtubules out in all directions probing the cytoplasm for a kinetochore The nuclear membrane which is composed of intermediate filaments breaks down The deterioration of the nuclear membrane occurs in Prophase In Metaphase the duplicated chromosomes all line up along the middle of the cell In Anaphase there are two kinds of microtubules Kinetochore microtubules which allow for separation of chromatids Polar microtubules whose ends push against one another to result in cell elongation Transition from anaphase to telophase initiates the dephosphorylation of many proteins that were phosphorylated at prophase Lamin s are dephosphorylated causing the reformation of the nuclear membrane In cytokinesis signals from chromosomes induce the formation of a contractile ring around the cell s cortex halfway between the two cells


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