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January 13, 2015 - Cell Division

by: Nicolle De Roeck

January 13, 2015 - Cell Division BIOL 11100 - Fundamentals of Biology II

Nicolle De Roeck
GPA 3.1
Fundamentals of Biology II
Dr. David Bos

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About this Document

Annotated lecture notes of Dr. Bos' lecture on January 13, 2015.
Fundamentals of Biology II
Dr. David Bos
One Day of Notes
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This 2 page One Day of Notes was uploaded by Nicolle De Roeck on Saturday January 24, 2015. The One Day of Notes belongs to BIOL 11100 - Fundamentals of Biology II at Purdue University taught by Dr. David Bos in Spring2015. Since its upload, it has received 207 views. For similar materials see Fundamentals of Biology II in Science at Purdue University.

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Date Created: 01/24/15
Why cells grow and divide Cells have a molecular system to control how much they grow and divide o It is genetically programmed and complex 9 lHWl reA U om allusion In multicellular organisms decisions to grow and divide made by quotcommitteequot 0 Other cells have in uence Ml dlbom gals cuff M aan ml Why cellular reproduction MD as 18mm Cell dlv1s1on 1s a key element of llfe anur glusease aenacl aglngk 02 5 a babg Responsive to environmental conditions gm wouWxizr r mmd Environment and lifestyle can in uence cell growth an division rates 0 May affect gene expression calrm 052M on 0 b 0 May cause mutations or mm mm 0 Ex Smoking vpremature aging Signals for cell growth and divisioneomcKm comm CM 0 MO Cell size and nutrition bios enough mum Malacca Condition of chromosomes 00 mamlg mutatlom gt no dJN39Rlon f Density dependent inhibitioncontact inhibition Ot wallow roomoucvkln Mar Mb Signals from other cells growth factors mwbors hormonal Cell growth genes MKva Mam mu 1 9 leastt39Ne wasnm Protooncogenes normal signals that stimulate cell growth and division 0 EX Growth factors and GF receptors r MA l o Cal1Cer 0 Oncogenes are mutated abnormal protooncogenes that are overactive Tumor suppressor genes normal signals that slowinhibit cell growth and division 0 Often function in detecting damaged cellDNA EWWW M Smut MW MFA o Lossimpaired TSG function leads to tumor growth Mum to Adi 6W3 Fall to balance normal stlmulatory s1gnals m CBWM WMW Swan Jreo mudl Cell growth accelerators and llllllbltOl SMWaz m Oncogenes over stlmulate cell growth and dlv1s10n Tumor suppressor genes slow growth and cell division T333 lelb tboncoe3 IWA Tumors and cancer am Wed up 7 All tumors have lost control of the cell cycle quotstraws 32mm Cancercausing mutations arise due to lifestyle and environmental factors 70 andor W 0le 60 0 Smoking diet alcohol exercise age at rst reproduction womenk Jm 0 Several genetic mutations are needed to lose control of cell cycle and cause cancer ovasad muAmtz cw dimion Promm


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