exam 3 notes
exam 3 notes BIOL 3303 - 001
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This 3 page Class Notes was uploaded by Danielle Banks on Thursday November 12, 2015. The Class Notes belongs to BIOL 3303 - 001 at University of Texas at Arlington taught by Perry Fuchs in Fall 2015. Since its upload, it has received 41 views. For similar materials see DRUGS AND BEHAVIOR in Biology at University of Texas at Arlington.
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Date Created: 11/12/15
Chapter 10 : Early intro and marketing of cigarettes Tar, carbon monoxide Action of nicotine Risks of tobacco use Pharmacology of nicotine : 1. Absorption and elimination -inhalation is very effective -deactivated by the liver before exertion by the kidney - decrease in hungry 2. Physiological effects - mimics Ach -releases adrenaline -inhibits hunger contractions -Constriction of blood vessels Nicotine is working under possible mechanism underlying nicotine addiction Conclusions from 1988 general surgeons report 1. Cigarettes and other tobacco products are ADDICTIVE 2. Nicotine is the drug in tobacco tht cause addiction 3. The pharmacology and behavioral processes that determine tobacco addiction are similar to those that determine addiction to drugs such as heroin and cocaine Why are these products on the market?? -marketing 4. depends on smoking , trying to quiet Leaves your body in 48 hours of nicotine Caffeine 1. Coffee 2. Tea (theophylline) 3. Chocolate (theobromine) ( These are three natural sources) 4. Caffeine belongs to a family of compounds called XANTHINES 5. Other sources of caffeine so Soft Drinks 6. Then over the counter drugs and bars of soap Chapter 11 - Caffeine as a drug - Absorption is rapid (30min) half life is round 3 hrs - Little tolerance - Both physical and psychological dependence Mechanism of action : Blocks brain receptors for Adenosine (changes things in the cell , cause relaxtion) Physiological effects : 1. Low doses: increased activity of the cortex 2. High doses: affect on autonomic centers Behavioral effect: 1. Increased attention and vigilance 2. Does not reverse alcohol intoxication Health Risks: 1. Research is inconclusive 2. Acute toxicity called caffeinism 3. Lethal doses 80 to 100 cups of coffee Anabolic Steroids and Drug Abuse in Sports 1. Historical use of drugs in sports -early Greek Olympians , mushrooms -1800’’s early 1900 cocaine, caffeine, strychnine -1940’s and 1950 amphetamine -1950 use of steroids 2. Steroids , Ergogenic action based on : - Androgenic effect: development of male sex characteristics - Anabolic effect: increase muscle mass 3. Hazards of anabolic steroids - Effect on hormone system -psychological problems Megorexia- Roid rage - Premature closing of growth plates - Liver dysfunction 4. Additional Hormonal and Other Manipulations - Human Growth Hormone - Creation - Androstenedione - Dehydroepiandrosterone ( DHEA) - Erythropoietin(EPO) Uranalysis Methods 1. ENZYME Immununoassy (EIA) 2. Gas Chromatography Mass Spectrometry Glues , Solvents and other Inhalants - Three major groups of inhalants 1. Gaseous anesthetics A. Nitrous Oxide B. Ether 2. Volatile Solvents : Risk of kidney damage , Brain damage , peripheral , Nerve damage , bad headaches , serious risk of suffocation 3. Nitrites : A. Amyl nitrites , B .Butyl Syomtoms : spots or sores around mouth , chemical breath , drunk and dizzy appearance , loss of appetite
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