Week 1 Bio Notes
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This 2 page Class Notes was uploaded by Nate Dickstein on Friday January 30, 2015. The Class Notes belongs to 105 at University of Massachusetts taught by Gerald Downes, Duncan Irschick, Jeffrey Podos in Winter2015. Since its upload, it has received 92 views.
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Date Created: 01/30/15
Class 112115 About Class see syllabus for more details 0 3 different teachers 0 review quizzes on friday infinite tries within a 7 day window that the quiz is up 0 understanding different social and cultural phenomena and issues from a biological perspective 0 CNSD brain or spinal cord dysfunction caused by trauma or disease includes paralysis concussion CTE stroke Alzheimer s disease Parkinson s disease and Lou Gehrig s disease Class 212315 o Neurological disordersdiseases are commonplace and prevalent in society 0 CNSD includes brain or spinal cord 0 Paralysis Eric Legrande football player got hit and became paralyzed from the neck down fractured C3 and C4 cervical vertebrae quadriplegic put on respirator o CNS central nervous system communication network of the body transmits signals between different parts of the body 2 different parts peripheral nervous system nerves outside brain spinal cord central nervous system brain and spinal cord 0 Spinal cord carries messages between brain and body allows brain to give motor commands to the body spinal cord can be damaged due to injury and genetic disorders what protects the spinal cord from injury bones 33 vertebrae split into 4 sections cervical vertebrae thoracic vertebrae lumbar vertebrae sacrum coccyx membranes surround spinal cordleather like fluid spinal cord is suspended in fluid 0 SCI spinal cord injury trauma 1012000 new cases per year most common causes motor vehicle accidents 40 sports 8 falls violence alcohol involved in 25 spinal cord injuries disease cancer arthritis infection the higher up the injury occurs the more affected the person will be 2 types complete injury spinal cord is cut at the affected area incomplete injury spinal cord is not completely cut off but just damages at the affected area 0 effects of SCI respiratory problems abnormal heartbeat muscle spasms pain loss of bladder control loss of sexual function what happens when the spinal cord is injured spinal shock initial ces neurons and their extensions axons are ruptured swelling causes interference with electrical activity secondary injury what damage occurs after the initial injury occurs invasion of immune cells inflammation many cells selfdestruct excess neurotransmitters How is SCI treated unlike PNS SC and brain cells have very limited capacity to regenerate in humans cells themselves have limited capacity to regrow and the environment outside of cells actively inhibits regrowth current treatments aren39t great alignment steroids limit inflammation physical therapy to maintain muscle tone Eric Legrande has regained some muscle control in his arms enabling him to do some gross movements also able to come off the respirator and breathe at his own pace New therapies being researched vast majority of SCI research is funded by grants from the federal government NIH national institute of health strategies protects surviving cells replace damaged cells stimulate growth retrain spinal cord circuits circumvent damaged spinal cord modern near future implementation of these strategies