Cardura, a drug used to treat hypertension, is synthesized as shown here. Br Br OH OH A

Chapter 16, Problem 84

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Cardura, a drug used to treat hypertension, is synthesized as shown here. Br Br OH OH A B O O + + CH3OH K2CO3 KOH HCl H2O O O O O Cardura O OCH3 C OCH3 a. Identify the intermediate (A) and show the mechanism for its formation. b. Show the mechanism for conversion of A to B. Which would be formed more rapidly, A or B?

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