As shown in Figure 23.4, the Claisen reaction is reversible. That is, a b-keto ester can
Chapter 23, Problem 23.12(choose chapter or problem)
As shown in Figure 23.4, the Claisen reaction is reversible. That is, a b-keto ester can be cleaved by base into two fragments. Using curved arrows to indicate electron flow, show the mechanism by which this cleavage occurs. 1 equiv. NaOH Ethanol O C O C C O OEt C O H H + H OEt 3C C O
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