Diethylstilbestrol (DES) has estrogenic activity even though it is structurally unrelated to steroids. Once used as an additive in animal feed, DES has been implicated as a causative agent in several types of cancer. Show how DES can be drawn so that it is sterically similar to estradiol. Estradio
Here’s what to take from this exercise: When asked to rate, people generate ratings even if they have very little information other than what a person looks like (as opposed to refusing to rate something they are unqualified to do). Disagreement arises from people using different information to generate their ratings. There is the most discretion in what information people use when you give no guidance at all—just a scale 1-10 with few words describing it. Disagreement is reduced with more detail given about what performance means in terms of acting behaviors and about what the different levels of the rating scale mean in terms of example behaviors. Disagreement is most reduced when they have all of t
