In the chemical synthesis of DNA and RNA, hydroxyl groups are normally convertedto
Chapter 21, Problem 21.48(choose chapter or problem)
In the chemical synthesis of DNA and RNA, hydroxyl groups are normally convertedto triphenylmethyl (trityl) ethers to protect the hydroxyl group from reaction with otherreagents. (a) Why are triphenylmethyl ethers so readily hydrolyzed by aqueous acid?(b) How might the structure of the triphenylmethyl group be modified to increase ordecrease its acid sensitivity?
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