An herb for depression? Does the herb Saint-Johns-wort relieve majordepression? Here are

Chapter 0, Problem 9.46

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An herb for depression? Does the herb Saint-Johns-wort relieve majordepression? Here are some excerpts from the report of a study of this issue.15 Thestudy concluded that the herb is no more effective than a placebo.(a) Design: Randomized, double-blind, placebo-controlled clinical trial. . . . Aclinical trial is a medical experiment using actual patients as subjects. Explain themeaning of each of the other terms in this description.(b) Participants...were randomly assigned to receive either Saint-Johns-wortextract (n = 98) or placebo (n = 102). . . . The primary outcome measure was therate of change in the Hamilton Rating Scale for Depression over the treatmentperiod. Based on this information, use a diagram to outline the design of thisclinical trial.

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