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An herb for depression? Does the herb SaintJohns-wort relieve major depression? Here is

Chapter 4, Problem R4.9

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QUESTION:

An herb for depression? Does the herb SaintJohns-wort relieve major depression? Here is an excerpt from the report of a study of this issue: Design: Randomized, Double-Blind, PlaceboControlled Clinical Trial. The study concluded that the difference in effectiveness of Saint-Johnswort and a placebo was not statistically significant.

(a) How did the design of this experiment account for the placebo effect?

(b) Explain the purpose of the random assignment.

(c) Why is a double-blind design a good idea in this setting?

(d) Explain what not statistically significant means in this context.

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QUESTION:

An herb for depression? Does the herb SaintJohns-wort relieve major depression? Here is an excerpt from the report of a study of this issue: Design: Randomized, Double-Blind, PlaceboControlled Clinical Trial. The study concluded that the difference in effectiveness of Saint-Johnswort and a placebo was not statistically significant.

(a) How did the design of this experiment account for the placebo effect?

(b) Explain the purpose of the random assignment.

(c) Why is a double-blind design a good idea in this setting?

(d) Explain what not statistically significant means in this context.

ANSWER:

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