Identify which of these designs is most appropriate for the given experiment: completely randomized design, randomized block design or matched pairs design.
Lisinipril Lisinipril is a drug designed to lower blood pressure. In a clinical trial of Lisinipril, blood pressure levels of subjects are measured before and after they have been treated with the drug.
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Given, Lisinopril is a drug designed to lower blood pressure. In a clinical trial of Lisinopril, blood pressure levels of subjects are measured before and after they have been treated with the drug.
Matched pairs design : is a special case of a randomized block design. It can be used when the experiment has only two treatment conditions; and subjects can be grouped into pairs, based on some blocking variable. Then, within each pair, subjects are randomly assigned to different treatments.
A matched pairs design would be the best selection for this scenario because the effectiveness of the drug is measured by its effect on different people. The blood pressure of the patients are measured before and after the drug.