Following is a series of anorexics (appetite
Chapter 23, Problem 23.65(choose chapter or problem)
Following is a series of anorexics (appetite suppressants). As you study their structures, you will surely be struck by the sets of characteristic structural features. NH2 Cl Ph Me NH2 (a) Ph N Ph (b) (c) Amphetamine Benzphetamine Chlorphentermine O Cl N H CN N H Ph (d) (e) NEt2 Ph Chlobenzorex Diethylpropion (f) Ph Fenproporex N H (g) Ph Methamphetamine NH2 (h) Pentorex NH2 (i) Phentermine (a) Knowing what you do about the synthesis of amines, including the Ritter reaction ( 23.52), suggest a synthesis for each compound. (b) Which of these compounds are chiral?
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