In a variation of the Merrifield solid-phase peptide
Chapter 27, Problem 27.51(choose chapter or problem)
In a variation of the Merrifield solid-phase peptide synthesis, the amino group is protected by a fl uorenylmethoxycarbonyl (FMOC) group. This protecting group is removed by treatment with a weak base such as the secondary amine, piperidine. Write a balanced equation and propose a mechanism for this deprotection. C H O CH2OC9NHCHCOOH R Fluorenylmethoxycarbonyl (FMOC) group
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