?The drug cisplatin is used to treat various forms of cancer in humans. As with many
Chapter 29, Problem 29.1(choose chapter or problem)
The drug cisplatin is used to treat various forms of cancer in humans. As with many other drugs, the difficult part in designing the cisplatin molecule was to have a structure that ensures transport into the cell. The equilibrium reaction that takes place in the body when cisplatin is administered is
Which form of cisplatin would you expect to exist inside the cell (where chloride concentrations are small)? Which form of cisplatin would you expect to exist outside the cell (where chloride concentrations are high)? Which form—cisplatin or monoaquacisplatin—enters the cell most readily? Why?
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