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Show how you would synthesize the following primary

Organic Chemistry | 8th Edition | ISBN: 9780321768414 | Authors: L.G. Wade Jr ISBN: 9780321768414 33

Solution for problem 13P Chapter 10

Organic Chemistry | 8th Edition

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Organic Chemistry | 8th Edition | ISBN: 9780321768414 | Authors: L.G. Wade Jr

Organic Chemistry | 8th Edition

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Problem 13P

Show how you would synthesize the following primary alcohols by adding an appropriate Grignard reagent to formaldehyde.

Step-by-Step Solution:

Solution 13P:

Here, we are going to propose the mechanism for the  synthesize the following primary alcohols by adding an appropriate Grignard reagent to formaldehyde.

The organomagnesium halides, of empirical formula R-Mg-X are called Grignard reagents by the name of  French chemist Victor Grignard. Grignard reagents can be obtained from the reaction of an alkyl halide with magnesium metal in presence of  dry (anhydrous) ether solvent, which is needed to solvate and stabilize the Grignard reagent as it forms.

R-X + Mg → R-Mg-X

Grignard reagent has been used for the synthesis of alcohol.

Step 1: Grignard reagent reagent attacks the carbonyl carbon of the formaldehyde

Step2: Water or dilute acid is added to protonate the alkoxide and give the alcohol.

Step 2 of 3

Chapter 10, Problem 13P is Solved
Step 3 of 3

Textbook: Organic Chemistry
Edition: 8
Author: L.G. Wade Jr
ISBN: 9780321768414

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Show how you would synthesize the following primary