Solution Found!
Show how you would use Grignard syntheses to prepare the
Chapter 2, Problem 39SP(choose chapter or problem)
Show how you would use Grignard syntheses to prepare the following alcohols from the indicated starting materials and any other necessary reagents.
(a) octan-3-ol from hexanal, \(\mathrm{CH}_{3}\left(\mathrm{CH}_{2}\right)_{4} \mathrm{CHO}\)
(b) octan-1-ol from 1-bromoheptane
(c) 1-cyclohexylethanol from acetaldehyde, \(\mathrm{CH}_{3} \mathrm{CHO}\)
(d) 2-cyclohexylethanol from bromocyclohexane
(e) benzyl alcohol \(\left(\mathrm{Ph}-\mathrm{CH}_{2}-\mathrm{OH}\right)\) from bromobenzene \(\text { (Ph - Br) }\)
(g) cyclopentylphenylmethanol from benzaldehyde \((\mathrm{Ph}-\mathrm{CHO})\)
Equation Transcription:
Text Transcription:
CH3(CH2)4CHO
CH_3CHO
(Ph-CH2-OH)
(Ph-Br)
OH
CH_3
CH_3
OCH_2CH_3
(Ph-CHO)
Questions & Answers
QUESTION:
Show how you would use Grignard syntheses to prepare the following alcohols from the indicated starting materials and any other necessary reagents.
(a) octan-3-ol from hexanal, \(\mathrm{CH}_{3}\left(\mathrm{CH}_{2}\right)_{4} \mathrm{CHO}\)
(b) octan-1-ol from 1-bromoheptane
(c) 1-cyclohexylethanol from acetaldehyde, \(\mathrm{CH}_{3} \mathrm{CHO}\)
(d) 2-cyclohexylethanol from bromocyclohexane
(e) benzyl alcohol \(\left(\mathrm{Ph}-\mathrm{CH}_{2}-\mathrm{OH}\right)\) from bromobenzene \(\text { (Ph - Br) }\)
(g) cyclopentylphenylmethanol from benzaldehyde \((\mathrm{Ph}-\mathrm{CHO})\)
Equation Transcription:
Text Transcription:
CH3(CH2)4CHO
CH_3CHO
(Ph-CH2-OH)
(Ph-Br)
OH
CH_3
CH_3
OCH_2CH_3
(Ph-CHO)
ANSWER:
Solution 39SP
(a) 3-octanol from CHO
Here two more carbon atom is needed, so the Grignard reagent should be of two carbon reagent.
(b) 1-octanol from 1-bromoheptane