Solution Found!
Devise a synthesis for each compound, starting with
Chapter 2, Problem 52SP(choose chapter or problem)
Problem 52SP
Devise a synthesis for each compound, starting with methylenecyclohexane and any other reagents you need.
(a) 1-methylcyclohexanol
(b) cyclohexylmethanol
(c) 1-(hydroxymethyl)cyclohexanol
(d) trans-2-methylcyclohexanol
(e) 2-chloro-1-methylcyclohexanol
(f) 1-(phenylmethyl)cyclohexanol
Questions & Answers
QUESTION:
Problem 52SP
Devise a synthesis for each compound, starting with methylenecyclohexane and any other reagents you need.
(a) 1-methylcyclohexanol
(b) cyclohexylmethanol
(c) 1-(hydroxymethyl)cyclohexanol
(d) trans-2-methylcyclohexanol
(e) 2-chloro-1-methylcyclohexanol
(f) 1-(phenylmethyl)cyclohexanol
ANSWER:
Solution:
Step 1
(a) Synthesis of 1-methylcyclohexanol:-
1-methylcyclohexanol can be prepared from cyclohexanone in presence of mercury acetate (Hg(OAC)2)and sodium borohydride (NaBH4)
(cyclohexanone) (1-methylcyclohexanol)