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Show how you would convert propan-1-ol to the following

Chapter 3, Problem 10P

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QUESTION:

Problem 10P

Show how you would convert propan-1-ol to the following compounds using tosylate intermediates. You may use whatever additional reagents are needed.

(a) 1-bromopropane

(b) propan-1-amine, CH3CH2CH2NH2

(c)CH3CH2CH2OCH2CH3 ethyl propyl ether

(d) CH3CH2CH2CN butyronitrile

Questions & Answers

QUESTION:

Problem 10P

Show how you would convert propan-1-ol to the following compounds using tosylate intermediates. You may use whatever additional reagents are needed.

(a) 1-bromopropane

(b) propan-1-amine, CH3CH2CH2NH2

(c)CH3CH2CH2OCH2CH3 ethyl propyl ether

(d) CH3CH2CH2CN butyronitrile

ANSWER:

Answer :

Tosylate esters (tosylates) are typically formed from alcohols with reaction with Ts-Cl and pyridine (py)Tosylate groups undergo a variety of SN2 reactions..

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