Methanol and ethanol are oxidized by alcohol

Chapter 20, Problem 25QP

(choose chapter or problem)

Methanol and ethanol are oxidized by alcohol dehydrogenase. When ethanol is oxidized, it becomes acetaldehyde, which can be converted to acetic acid in the liver. However, when methanol is oxidized, it forms formaldehyde. In methanol poisoning, ethanol is given intravenously to prevent the formation of formaldehyde that has toxic effects.

a. Draw the condensed structural formulas for methanol and ethanol.

b. Would ethanol compete for the active site or bind to a different site on the enzyme?

c. Would ethanol be a competitive or noncompetitive inhibitor of methanol oxidation?

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