Epibatidine is one of the alkaloids that the Ecuadorian
Chapter 20, Problem 33CI(choose chapter or problem)
Epibatidine is one of the alkaloids that the Ecuadorian poison dart frog (Epipedobates tricolor) secretes through its skin. Natives of the rainforest prepare poison darts by rubbing the tips on the skin of the poison dart frogs. The effect of a very small amount of the poison can paralyze or kill an animal. As a pain reliever, epibatidine is 200 times more effective than morphine. Although a therapeutic dose has been calculated as 2.5 µg/kg, epibatidine has adverse effects. It is expected that more research to chemically modify the epibatidine molecule will produce an important pain reliever. (6.4, 6.5, 18.3) Natives in the South American rainforests obtain poison for blow darts from the alkaloids secreted by poison dart frogs.a. What two heterocyclic amines are in the structure of epibatidine?________________b. What is the molecular formula of epibatidine?________________c. What is the molar mass of epibatidine?________________d. How many grams of epibatidine would be given to a 60. kg person if the dose is 2.5 µg/kg?________________e. How many molecules of epibatidine would be given to a 60. kg person for the dose in part d?
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