a. A base substitution changes a codon in the mRNA for an

Chapter 21, Problem 61QP

(choose chapter or problem)

a. A base substitution changes a codon in the mRNA for an enzyme from GCC to GCA. Why is there no change in this amino acid in the protein?________________b. In sickle cell anemia, a base substitution in hemoglobin results in the replacement of glutamic acid (a polar acidic amino acid) with valine. Why does the replacement of one amino acid cause such a drastic change in biological function?

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