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Sickle-cell anemia is caused by a genetic defect that sub­stitutes valine for glutamic

Introductory Chemistry | 5th Edition | ISBN: 9780321910295 | Authors: Nivaldo J Tro ISBN: 9780321910295 34

Solution for problem 92P Chapter 19

Introductory Chemistry | 5th Edition

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Introductory Chemistry | 5th Edition | ISBN: 9780321910295 | Authors: Nivaldo J Tro

Introductory Chemistry | 5th Edition

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Problem 92P

Sickle-cell anemia is caused by a genetic defect that substitutes valine for glutamic acid at one position in two of the four chains of the hemoglobin protein. The result is a decrease in the water solubility of hemoglobin. Examine the structures of valine and glutamic acid in Table 19.2 and

explain why this might be so.

Step-by-Step Solution:

Solution:

Step 1

Sickle cell anemia is caused by a genetic defect that substitutes valine for glutamic acid in a specific position in the hemoglobin protein. The structure of the two amino acids are,

Step 2 of 2

Chapter 19, Problem 92P is Solved
Textbook: Introductory Chemistry
Edition: 5
Author: Nivaldo J Tro
ISBN: 9780321910295

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Sickle-cell anemia is caused by a genetic defect that sub­stitutes valine for glutamic