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Sickle-cell anemia is caused by a genetic defect that substitutes valine for glutamic
Chapter 19, Problem 92P(choose chapter or problem)
Sickle-cell anemia is caused by a genetic defect that substitutes valine for glutamic acid at one position in two of the four chains of the hemoglobin protein. The result is a decrease in the water solubility of hemoglobin. Examine the structures of valine and glutamic acid in Table \(19.2\) and
explain why this might be so.
Equation Transcription:
Text Transcription:
19.2
Questions & Answers
QUESTION:
Sickle-cell anemia is caused by a genetic defect that substitutes valine for glutamic acid at one position in two of the four chains of the hemoglobin protein. The result is a decrease in the water solubility of hemoglobin. Examine the structures of valine and glutamic acid in Table \(19.2\) and
explain why this might be so.
Equation Transcription:
Text Transcription:
19.2
ANSWER:Solution:
Step 1
Sickle cell anemia is caused by a genetic defect that substitutes valine for glutamic acid in a specific position in the hemoglobin protein. The structure of the two amino acids are,