Solution Found!
Show how you would make the following ethers, using only
Chapter 24, Problem 29SP(choose chapter or problem)
Problem 29SP
Show how you would make the following ethers, using only simple alcohols and any needed reagents as your starting materials.
(a) 1-methoxybutane
(b) 2-ethoxy-2-methylpropane
(c) benzyl cyclopentyl ether
(d) trans-2-methoxycyclohexanol
(e) the TIPS ether of (d)
(f) cyclohexyl cyclopentyl ether
Questions & Answers
QUESTION:
Problem 29SP
Show how you would make the following ethers, using only simple alcohols and any needed reagents as your starting materials.
(a) 1-methoxybutane
(b) 2-ethoxy-2-methylpropane
(c) benzyl cyclopentyl ether
(d) trans-2-methoxycyclohexanol
(e) the TIPS ether of (d)
(f) cyclohexyl cyclopentyl ether
ANSWER:
Solution:
Here we have to write the synthesis of following ethers:-
Step 1
(a) Synthesis of 1-methoxybutane
1-methoxybutane can be prepared from butan-ol. In this reaction butanol in presence of metallic sodium forms an intermediate product, which on addition with methyl bromide gives 1-methoxybutane with sodium bromide.
+ NaBr