Solution Found!
Bioavailability When a drug is given intravenously, the
Chapter 7, Problem 43E(choose chapter or problem)
Bioavailability When a drug is given intravenously, the concentration of the drug in the blood is \(C_{i}(t)=250 e^{-0.08 t}\), for \(t \geq 0\). When the same drug is given orally, the concentration of the drug in the blood is \(C_{0}(t)=200\left(e^{-0.081}-e^{-1.8 t}\right)\), for \(t \geq 0\). Compute the bioavailability of the drug.
Questions & Answers
QUESTION:
Bioavailability When a drug is given intravenously, the concentration of the drug in the blood is \(C_{i}(t)=250 e^{-0.08 t}\), for \(t \geq 0\). When the same drug is given orally, the concentration of the drug in the blood is \(C_{0}(t)=200\left(e^{-0.081}-e^{-1.8 t}\right)\), for \(t \geq 0\). Compute the bioavailability of the drug.
ANSWER:Problem 43E
Bioavailability When a drug is given intravenously, the concentration of the drug in the blood is , for t ≥ 0. When the same drug is given orally, the concentration of the drug in the blood is
, for t ≥ 0. Compute the bioavailability of the drug.
Solution
Step 1
In this problem we need to compute the bioavailability of drug.
Given : when drug is given intravenously, the concentration of the drug in blood is .
When the same drug is given orally, the concentration of the drug in blood is
Thus the bioavailability of the drug is … (1)
Let us first find and