Medication used to treat & certain condition is

Chapter 4, Problem 7SE

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QUESTION:

Medication used to treat a certain condition is administered by syringe. The target dose in a particular application is μ. Because of the variations in the syringe, in reading the scale, and in mixing the fluid suspension, the actual dose administered is normally distributed with mean μ and variance \(\sigma^{2}\).

a. What is the probability that the dose administered differs from the mean μ by less than σ?

b. If X represents the dose administered, find the value of z so that \(P(X<\mu+z \sigma)=0.90\).

c. If the mean dose is 10 mg, the variance is \(2.6 \mathrm{mg}^{2}\), and a clinical overdose is defined as a dose larger than 15 mg, what is the probability that a patient will receive an overdose?

Equation transcription:

Text transcription:

\sigma^{2}

P(X<\mu+z \sigma)=0.90

2.6 {mg}^{2}

Questions & Answers

QUESTION:

Medication used to treat a certain condition is administered by syringe. The target dose in a particular application is μ. Because of the variations in the syringe, in reading the scale, and in mixing the fluid suspension, the actual dose administered is normally distributed with mean μ and variance \(\sigma^{2}\).

a. What is the probability that the dose administered differs from the mean μ by less than σ?

b. If X represents the dose administered, find the value of z so that \(P(X<\mu+z \sigma)=0.90\).

c. If the mean dose is 10 mg, the variance is \(2.6 \mathrm{mg}^{2}\), and a clinical overdose is defined as a dose larger than 15 mg, what is the probability that a patient will receive an overdose?

Equation transcription:

Text transcription:

\sigma^{2}

P(X<\mu+z \sigma)=0.90

2.6 {mg}^{2}

ANSWER:

Answer:

Step 1 of 3:

(a)

In this question we have asked to find the probability that the dose administered differs from the mean   by less than .

Actual dose administered is normally distributed with mean  and variance .

We know that if X is a random variable whose probability density function is normal with mean  and variance , then we can write as X  

Where N is called the normal distribution ( also called the Gaussian distribution)  whose probability density function can be written as

Figure 1 represent a plot of the normal distribution (probability distribution function plot) with mean  and standard deviation

Figure 1 Probability density function of a normal random variable with mean

and standard deviation

Sometimes we sample any population from a normal population with value of  mean 0 and standard deviation 1 and this normal population is called the standard normal population and we represent it by the “z-score” of x.

In the question we are asking the probability that the dose administered differs from the mean   by less than .

So from the figure we can find the probability that a normal random variable is within one standard deviation  of its mean  is the area under the normal curve between and . (using table)

Area to the left of z = - 1 is 0.1587

Area to the left of z =  1 is 0.8413

Hence the area between this 0.8413 - 0.1587 = 0.6826 and it is also visible from the figure 1.

So the probability that the dose administered differs from the mean  by less  is equal to 0.6826.


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