Transepidermal water loss (TEWL) is a measure of the rate

Chapter 5, Problem 3E

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Transepidermal water loss (TEWL) is a measure of the rate that water crosses the skin through diffusion and evaporation. In general, damaged skin has a higher TEWL than non damaged skin. A report submitted to the U.S. Food and Drug Administration (Thera- peutic Equivalence of Topical Products, A. Bunge,  B. N’Dri-Stempfer, et al., 2007) described an experiment in which the outer layer of skin on a small  area of the forearm was partially removed in order to measure the concentration of a certain drug. TEWL (in g/\(\mathrm{cm}^{2}) per hour) was measured both before and after skin removal. The results for 10 individuals were as follows.

Find a 98% confidence for the increase in TEWL.

 Equation transcription:

Text transcription:

\mathrm{cm}^{2}

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