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Solved: Show how you would accomplish the following

Chapter 12, Problem 7P

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QUESTION:

Show how you would accomplish the following synthetic conversions by adding an organolithium reagent to an acid.

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QUESTION:

Show how you would accomplish the following synthetic conversions by adding an organolithium reagent to an acid.

ANSWER:

Solution 7P

  1. Dianion is protonated in presence of  to form hydrate and followed by removal of water to form target product.

(b)

Bromocyclopentane reacts with two equivalents of lithium to form one equivalent of cyclopentyl lithium.

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