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Show how you would accomplish the following multistep
Chapter 14, Problem 39SP(choose chapter or problem)
Show how you would accomplish the following multistep syntheses. You may use any additional reagents and solvents you need.
Questions & Answers
QUESTION:
Show how you would accomplish the following multistep syntheses. You may use any additional reagents and solvents you need.
ANSWER:
Solution:
Here we have to show the following synthesis:-
Step 1
2-phenylethanol can be converted into 3-phenylpropanoic acid by the following 3 steps. In the 1st step 2-phenyl ethanol in presence of thionyl bromide (SOBr2) forms 2-phenylethyl bromide along with HBr and SO2. In the 2nd step 2-phenylethyl bromide will react in presence of Mg and dry ether and forms 2-phenylethyl magnesium bromide which in presence of CO2 and hydronium ion forms 3-phenylpropanoic acid as the product.