Solved: Catalysis (Section)The enzyme carbonic anhydrase

Chapter , Problem 85E

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Problem 85E

Catalysis (Section)

The enzyme carbonic anhydrase catalyzes the reaction CO2(g) + H2O(I)→HCO3 - (aq) + H+ (aq). In water, without the enzyme, the reaction proceeds with a rate constant of 0.039 s-1 at 25 °C. In the presence of the enzyme in water, the reaction proceeds with a rate constant of 1.0 x 106 s-1 at 25 °C. Assuming the collision factor is the same for both situations, calculate the difference in activation energies for the uncatalyzed versus enzyme-catalyzed reaction.

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