Suppose we have some optically pure -butyl acetate that has been "labeled" with the heavy \({ }^{18} O\) isotope at one oxygen atom as shown.
(a) Draw a mechanism for the hydrolysis of this compound under basic conditions. Predict which of the products will contain the \({ }^{18} O\) label. Also predict whether the butan- 2 -ol product will be pure , pure
, or racemized.
(b) Repeat part (a) for the acid-catalyzed hydrolysis of this compound.
(c) Explain how you would prove experimentally where the \({ }^{18} O\) label appears in the products. (\({ }^{18} O\) is not radioactive.
Equation transcription:
Text transcription:
^{18} O
Chemistry Lecture 7 Chapter 15: Chemical Equilibrium Dynamics of Chemical Reactions and Microscopic Reversibility Reactions can be reversible and dynamic when rate of forward and reverse reaction are equal reaction arrows in each direction can denote this Equilibrium does not mean same amount of reactant and product concentrations do not need to be equal can go in favor of products or reactants (can be determined by which you have relatively more of) an expression equilibrium constant =K eq (make sure its a capital K) equilibrium constant only changes when temperature changes Rate constant does not have to be equal for forward reaction and reverse reaction when equilibrium is reached, the concentration of the products and reactants no longer change Rules for calculating coefficients in front of the reactant turn into the exponents when plugging into equation products are always divided by reactants any products or reactants that are solid or liquid should not be included in the equation only include reactants and products in the gaseous or aqueous state The I.C.E. Table I inital concentration C change in concentration E equilibrium concentration The initial concentration of produc