Consider the relationship ln1K2 5 2DH RT 1 DS R The equilibrium constant for some hypothetical process was determined as a function of temperature (in kelvins) with the results plotted below. 1000 T(K) ln ( K) 10. 1.0 2.0 3.0 20. 30. 40. From the plot, determine the values of DH8 and DS8 for this process. What would be the major difference in the ln(K) versus 1/T plot for an endothermic process as compared to an exothermic process?
Ligand Binding: Oxygen Binding to Hemoglobin & Myoglobin • Hemoglobin and myoglobin are part of the same superfamily-‐ they have the same 3D structure but they do not have the same amino acid sequence (primary structure) • Hemoglobin has four subunits and myoglobin only have one-‐ this gives them different properties Ligand binding is extremely specific • A ligand is a molecule (smaller than a protein) that bind
