Answer: The isoelectric point of an amino acid is the pH
Chapter 21, Problem 21.154(choose chapter or problem)
The isoelectric point of an amino acid is the pH at which the molecule has no net charge. For glycine, that would be the pH at which virtually all glycine molecules are in the form 1H3NCH2CO2 2. If we assume that the principal equilibrium is 21H3NCH2CO2 2 34 H2NCH2CO2 2 1 1H3NCH2CO2H (i) then at equilibrium [H2NCH2CO2 2] 5 [1H3NCH2CO2H] (ii) Use this result and your answer to part c of Exercise 152 to calculate the pH at which Equation (ii) is true. This will be the isoelectric point of glycine.
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