Solve each equation. x 3 + 8 0
Degenerative Change with Age ● Body dimensions and composition, skin, hair, skeletal, vascular, respiratory, neurological, immunological, our senses...all change ● Involves gradual molecularlevel change, which then affects cell, tissue, organ, and/or system function. Body shape and size ● Peak body height in 20s, then gradual decline ● Peak weight in 40s, then gradual decline ● Peak BMI (weight/height^2) by 65, then decline. ● Decline in fatfree or lean mass (FFM), increase in fat (FM) ● Relocation of fat: men=guts women=hips/thighs Skin/Hair ● Reduced microcirculation ● Thinning and welling ● Hair folliclessweat glands Cardiovascular ● Reduced oxygen absorption ● Vascular stiffening/obstructions ● Reduced cardiac function MusculoSkeletal ● Spinal compression ● Calcium leaching ● Reduced bone production ● Muscle mass, fibers, enervation Guts ● Reduced organ elasticity ● Reduced mineral uptake ● Microflora changes ● Reduced peristalsis ● Reduced kidney function ● Bladder elasticity ● Sphincter enervation The Senses ● Lens discoloration ● Presbyopia ● cataracts/glaucoma ● Reduced sense of smell ● Reduced sense of touch Why try to understand why Or.. great excuses for biological research ● Helps people live longer..and longer and longer (extending life spanlongevity) ● Helps people age with better health (extending “health span”) ● Helps people look better Along the way (antiaging, unaging, and the pursuit of youth) Degenerative Change with Age ● Body dimensions and composition, skin, hair, skeletal, vascular, respiratory, neurological, immunological, our senses...all change ● Involves gradual molecularlevel change, which then affects cell, tissue, organ, and/or system function. Body shape and size ● Peak body height in 20s, then gradual decline ● Peak weight in 40s, then gradual decline ● Peak BMI (weight/height^2) by 65, then decline. ● Decline in fatfree or lean mass (FFM), increase in fat (FM) ● Relocation of fat: men=guts women=hips/thighs Skin/Hair ● Reduced microcirculation ● Thinning and welling ● Hair folliclessweat glands Cardiovascular ● Reduced oxygen absorption ● Vascular stiffening/obstructions ● Reduced cardiac function MusculoSkeletal ● Spinal compression ● Calcium leaching ● Reduced bone production ● Muscle mass, fibers, enervation Guts ● Reduced organ elasticity ● Reduced mineral uptake ● Microflora changes ● Reduced peristalsis ● Reduced kidney function ● Bladder elasticity ● Sphincter enervation The Senses ● Lens discoloration ● Presbyopia ● cataracts/glaucoma ● Reduced sense of smell ● Reduced sense of touch Why try to understand why Or.. great excuses for biological research ● Helps people live longer..and longer and longer (extending life spanlongevity) ● Helps people age with better health (extending “health span”) ● Helps people look better Along the way (antiaging, unaging, and the pursuit of youth)