Drug controlled-release rate study. Refer to the Drug

Chapter 11, Problem 82E

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QUESTION:

Drug controlled-release rate study. Refer to the Drug Development and Industrial Pharmacy (Vol. 28, 2002) drug controlled-release rate study, Exercise 11.17 (p. 615). Recall that data for six drug tablets were used to fit the simple linear model, \(E(y)=\beta_0+\beta_1 x\), where y =  drug release rate and x =  surface-area-to-volume ratio. An Excel/XLSTAT printout giving a 90% prediction interval for each of the n = 6 observations in the sample is shown above. Select an observation and give a practical interpretation for this prediction interval.

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QUESTION:

Drug controlled-release rate study. Refer to the Drug Development and Industrial Pharmacy (Vol. 28, 2002) drug controlled-release rate study, Exercise 11.17 (p. 615). Recall that data for six drug tablets were used to fit the simple linear model, \(E(y)=\beta_0+\beta_1 x\), where y =  drug release rate and x =  surface-area-to-volume ratio. An Excel/XLSTAT printout giving a 90% prediction interval for each of the n = 6 observations in the sample is shown above. Select an observation and give a practical interpretation for this prediction interval.

ANSWER:

Step 1 of 2

Let response variable (y) is drug release rate and the predictor variable (x) is surface area to volume ratio.

From the MINITAB output, let’s take the observation of surface area to volume as 1.05.

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