Adult-onset diabetes is known to be highly genetically determined. A study was done comparing frequencies of a particular allele in a sample of such diabetics and a sample of nondiabetics. The data are shown in the following table: Diabetic Normal Bb or bb 12 4 BB 39 49 Are the relative frequencies of the alleles significantly different in the two groups?

Sample Distributions (Chapter 10) Important definitions explained in these notes: Sample space Event Parameter Statistical inference The Law of Large Numbers Discrete Probability Models Continuous Probability Models Random Variable Random Variable X bar or xx Central Limit Theorem An unbiased estimator The Rules of Calculating Probabilities: All values between 0 and 1 If S is sample space of a probability model, then P(s)=1 Addition rule for disjoint events: if two events have no outcomes in common, the probability that one or the other occurs is the sum of their individual probabilities a. P(A or B) = P(A) +