Deformability of Arteries with Atherosclerosis DS 12.12.6

Chapter 12, Problem 12.12.6

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Deformability of Arteries with Atherosclerosis DS 12.12.6 contains the circumferential strains S and lesion areas L of n =12 specimens of human arterieswith atherosclerosis. This disease is commonly referred to as hardening of the arteries due to the accumulation of plaque on the artery walls. The lesion area measures the amount of plaque that has accumulated on the artery walls and can be thought of as the disease severity. The circumferential strain is a measure of the deformability of the artery tissue. A model that relates the circumferential strain S to the lesion area L is helpful in assessing the potential impact of various levels of atherosclerosis. (a) Show that the model S = 0 + 1 L appears to provide a good t to the data set. (b) After a suitable transformation of the variables, nd point estimates for 0 and 1. (c) Calculate two-sided 95% condence intervals for 0 and 1. (d) What is the predicted circumferential strain of an artery with a lesion area of 10.0 mm2?

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