Solved: Clinical Trial of Lipitor Lipitor is the trade

Chapter 11, Problem 19

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Clinical Trial of Lipitor Lipitor is the trade name of the drug atorvastatin, which is usedto reduce cholesterol in patients. (Until its patent expired in 2011, this was the largest-sellingdrug in the world, with annual sales of $13 billion.) Adverse reactions have been studied inclinical trials, and the table below summarizes results for infections in patients from differenttreatment groups (based on data from Parke-Davis). Use a 0.01 significance level to test theclaim that getting an infection is independent of the treatment. Does the atorvastatin treatmentappear to have an effect on infections?Placebo Atorvastatin 10 mg Atorvastatin 40 mg Atorvastatin 80 mgInfection 27 89 8 7No Infection 243 774 71 87

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