The first step in the synthesis of cis-(1)-sertraline is the reduction of the carboxylic
Chapter 19, Problem 19(choose chapter or problem)
The first step in the synthesis of \(cis -(+) - sertraline\) is the reduction of the carboxylic acid group of protected D-phenylglycine A to give a primary alcohol B. Which of the following reagents is used to reduce the carbonyl group?
(a) \(\mathrm{NaBH}_{4}\)
(b) \(\mathrm{H}_{2}, \mathrm{Pd} / \mathrm{C}\)
(c) \(LiAlH _{4}\)
(d) MeMgBr
Equation Transcription:
Text Transcription:
cis-(+)-sertraline
NaBH4
H2,Pd/C
LiAlH4
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