Brevianamide S, a potent antitubercular natural product, was recently isolated from a

Chapter 16, Problem 16.72

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Brevianamide S, a potent antitubercular natural product, was recently isolated from a marine sediment collected off the coast of China (Org. Lett. 2012, 14, 47704773). Predict the chemical shift and determine the multiplicity of each signal in the 1 H NMR spectrum for brevianamide S (chemical shifts have been provided in situations where the relevant benchmark values were not covered in this chapter). N N O O N NH N O O NH H H H H 4.1 ppm 7.4 ppm 7.7 ppm Brevianamide S

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