Given two complementary strands of DNA containing 100 base

Chapter 12, Problem 104AP

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Problem 104AP

Given two complementary strands of DNA containing 100 base pairs each, calculate the ratio of two separate strands to hydrogen-bonded double helix in solution at 300 K. (Hint: The formula for calculating this ratio is e−ΔE/RT, where ΔE is the energy difference between hydrogen-bonded double-strand DNAs and single-strand DNAs and R is the gas constant.) Assume the energy of hydrogen bonds per base pair to be 10 kJ/mol.

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