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Show how FriedelCrafts acylation might be used to synthesize the following compounds

Chapter 21, Problem PROBLEM 21-30

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QUESTION:

Show how Friedel–Crafts acylation might be used to synthesize the following compounds.

(a) acetophenone

(b) benzophenone

(c) n-butylbenzene

Questions & Answers

QUESTION:

Show how Friedel–Crafts acylation might be used to synthesize the following compounds.

(a) acetophenone

(b) benzophenone

(c) n-butylbenzene

ANSWER:

Step 1 of 4

Fridel-Crafts acylation:

The Friedel–Crafts Acylation reaction involves formation of a complex between the Lewis acid and the chlorine atom of the acid chloride. An acylium ion is formed by the cleavage of C-Cl bond of the complex. The acylium ion has a positive charge on the carbon and is resonance stabilized.

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