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Show how FriedelCrafts acylation might be used to synthesize the following compounds
Chapter 21, Problem PROBLEM 21-30(choose chapter or problem)
QUESTION:
Show how Friedel–Crafts acylation might be used to synthesize the following compounds.
(a) acetophenone
(b) benzophenone
(c) n-butylbenzene
Questions & Answers
QUESTION:
Show how Friedel–Crafts acylation might be used to synthesize the following compounds.
(a) acetophenone
(b) benzophenone
(c) n-butylbenzene
ANSWER:Step 1 of 4
Fridel-Crafts acylation:
The Friedel–Crafts Acylation reaction involves formation of a complex between the Lewis acid and the chlorine atom of the acid chloride. An acylium ion is formed by the cleavage of C-Cl bond of the complex. The acylium ion has a positive charge on the carbon and is resonance stabilized.