A number of substances containing positively polarized carbon atoms have been labeled

Chapter 1, Problem 50

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A number of substances containing positively polarized carbon atoms have been labeled ascancer suspect agents (i.e., suspected carcinogens or cancer-inducing compounds). It hasbeen suggested that the presence of such carbon atoms is responsible for the carcinogenicproperties of these molecules. Assuming that the extent of polarization is proportional tocarcinogenic potential, how would you rank the following compounds with regard to cancercausingpotency?(a) CH3Cl (b) (CH3)4Si (c) ClCH2OCH2Cl(d) CH3OCH2Cl (e) (CH3)3C1(Note: Polarization is only one of the many factors known to be related to carcinogenicity. Moreover,none of them shows the type of straightforward correlation implied in this question.)

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