Many drugs are sold as their hydrochloride salts (R2NH2 + Cl ), formed by reaction of an
Chapter 3, Problem 3.45(choose chapter or problem)
Many drugs are sold as their hydrochloride salts (R2NH2 + Cl ), formed by reaction of an amine (R2NH) with HCl. N H O H O N OH O acebutolol a. Draw the product (a hydrochloride salt) formed by reaction of acebutolol with HCl. Acebutolol is a blocker used to treat high blood pressure. b. Discuss the solubility of acebutolol and its hydrochloride salt in water. c. Offer a reason as to why the drug is marketed as a hydrochloride salt rather than a neutral amine.
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