The article Evaluation of a Ventilation Strategy to PreventBarotrauma in Patients at

Chapter 9, Problem 9

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The article Evaluation of a Ventilation Strategy to PreventBarotrauma in Patients at High Risk for Acute RespiratoryDistress Syndrome (New Engl. J. of Med., 1998: 355358)reported on an experiment in which 120 patients with similarclinical features were randomly divided into a control group and a treatment group, each consisting of 60 patients. The samplemean ICU stay (days) and sample standard deviation forthe treatment group were 19.9 and 39.1, respectively, whereasthese values for the control group were 13.7 and 15.8.a. Calculate a point estimate for the difference betweentrue average ICU stay for the treatment and controlgroups. Does this estimate suggest that there is a significantdifference between true average stays under thetwo conditions?b. Answer the question posed in part (a) by carrying out aformal test of hypotheses. Is the result different from whatyou conjectured in part (a)?c. Does it appear that ICU stay for patients given theventilation treatment is normally distributed? Explainyour reasoning.d. Estimate true average length of stay for patients given theventilation treatment in a way that conveys informationabout precision and reliability.

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