Tris(hydroxymethyl)aminomethane [(HOCH2)3CNH2, known as

Chapter 20, Problem 75P

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Problem 75P

Tris(hydroxymethyl)aminomethane [(HOCH2)3CNH2, known as TRIS] is a weak base used in biochemical experiments to make buffer solutions in the pH range of 7 to 9. A certain TRIS buffer has a pH of 8.10 at 25°C and a pH of 7.80 at 37°C. Why does the pH change with temperature?

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