Average drug dose. The concentration, C, of phenylbutazone, in micrograms per milliliter

Chapter 4, Problem 59

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Average drug dose. The concentration, C, of phenylbutazone, in micrograms per milliliter (g/mL), in the plasma of a calf injected with this anti-inflammatory agent is given approximately by where t is the number of hours after the injection and (Source: A. K. Arifah and P. Lees, Pharmacodynamics and Pharmacokinetics of Phenylbutazone in a) Given that this model is accurate for what is the initial dosage? b) What is the average amount of phenylbutazone in the calfs body for the time between 10 and 120 hours?

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