In 2005, J. Robin Warren and Barry J. Marshall shared the Nobel Prize in Medicine for discovery of the bacterium Helicobacter pylori, and for establishing experimental proof that it plays a major role in gastritis and peptic ulcer disease. The story began when Warren, a pathologist, noticed that bacilli were associated with the tissues taken from patients suffering from ulcers. Look up the history of this case and describe Warren's first hypothesis. What sorts of evidence did it take to create a credible theory based on it?
Solution 82AE: The causes for the disease like gastritis and ulcer is due to the bacterium which is present in the human stomach. This was discovered by J. Robin Warren and Barry J. Marshall in 2005.They hypothesized that ulcer in the stomach is accelerated due to the bacterium called Helicobacter pylori. The stomach ulcer is not because of excess acidity. In the beginning of science, it was a believed that ulcer is triggered due to the excessive acidity. It was the believed that bacteria can not stay in stomach due to such acids. Therefore the hypothesis was not accepted. After, the rejection of such a theory, Dr. Warren and Dr.Marshall tried to prove that the bacteria is responsible for such diseases.For that he consumed a beaker of water having Helicobacter pylori bacteria and after some time, he had been suffering from a severe stomach pain which is due the development of ulcer inside the stomach. Therefore, he had proved his hypothesis and made people to believe him. This evidence created a credible theory.