Metallic elements are essential components of many important enzymes operating within
Chapter 24, Problem 24.71(choose chapter or problem)
Metallic elements are essential components of many important enzymes operating within our bodies. Carbonic anhydrase, which contains Zn2+, is responsible for rapidly interconverting dissolved C02 and bicarbonate ion, HC03 -. The zinc in carbonic anhydrase is coordinated by three nitrogen-containing groups and a water molecule. The enzyme's action depends on the fact that the coordinated water molecule is more acidic than the bulk solvent molecules. Explain this fact in terms of Lewis acid-base theory (Section 16.11).
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